tangermeme

Biological sequence analysis for the modern age.

MIT License

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tangermeme - v0.2.0 Latest Release

Published by jmschrei 5 months ago

This release focuses on attribution methods and other utilities based on better using these attributions.

  • Stand-alone implementation of DeepLIFT/SHAP that fixes several small issues with the Captum implementation; bugs, improved batching and throughput for small models, etc.
  • Seqlet calling for identifying spans of high-attribution signal
  • Plotting and annotations of those plots
  • Altered API for saturation_mutagenesis to be more consistent with the results from deep_lift_shap.
  • Altered API for several functions to allow the passing in of a custom function to apply, e.g., for marginalize to allow passing in either predict or deep_lift_shap (or any other function) to apply before and after substituting in a motif of interest
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