MIT License
This is a Python reimplementation of the MATLAB code by Max W.K. Law: Optimally Oriented Flux (OOF) for 3D Curvilinear Structure Detection.
I haven't verified that it works exactly the same.
pip install git+https://github.com/fepegar/optimally-oriented-flux
oof input_file.nii.gz output_file.nii.gz